Endocrine Abstracts

Background: Type 2 diabetes (T2D) is a progressive disease. The gut microbiota has recently been identified as a new potential diabetes risk factor. Short-chain fatty acids (SCFAs) are organic fatty acids produced in the distal gut by bacterial fermentation of macrofibrous material that might improve T2D.Aims: To examine the effectiveness of glucagon-like peptide (GLP)-1 receptor agonist treatment on SCFAs, carbohydrate and lipid metabolism in patients w...

Background: Short-chain fatty acids (SCFAs) are organic fatty acids produced in the distal gut by bacterial fermentation of macrofibrous material. SCFAs play an important role in health and disease. They may reduce the risk of inflammatory diseases, type 2 diabetes, obesity, heart disease and other conditions.Aims: to examine the effectivenessof glucagon-like peptide (GLP)-1 receptor agonist and prebiotic treatment on SCFAs, carbohydrate metabolism in pa...

Purpose: To study the state of the microvasculature and tissue metabolism (according to the dynamics of the FAD and NADH coenzymes) using laser Doppler fluometry (LDF) and laser fluorescence spectroscopy (LFS) in patients with diabetes mellitus.Materials and methods: To implement the combined use of LDF and LFS methods, the Laser Diagnostic Device LAZMA ST was used (registration certificate of Roszdravnadzor No. RZN 2017/5844 of June 08, 2017).<p cla...

AimAnalyze a number of foreign sources to assess the risks of developing post-transplant diabetes mellitus (PTSD).Materials and methodsIn total, we analyzed more than 70 sources from Western Europe, East Asia and South Africa. Pancreatic β-cell dysfunction, impaired insulin secretion associated with the use of calcineurin inhibitors and inhibitors of the mammalian target of rapamycin complex 1 (mTORC1), ...